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Principles of Clinical Cannabinology

Get your digital or paperback copy of the handbook. 30+ pathologies covered with clinical trials and scientific references.

The resource healthcare professionals
need to prescribe medical cannabis


Chapter 1: The Endocannabinoid System
  • 1.1 Endocannabinoid System
  • 1.2 Endocannabinoid System and Pain
  • 1.3 The Endocannabinoid System in the Gastrointestinal Tract
  • 1.4 How the Endocannabinoid System regulates sexual activity and birth
  • 1.5 The Endocannabinoid System and the sleep-wake cycle: The role in insomnia
  • 1.6 Insight: Palmitoylethanolamide (PEA)
  • 1.7 Insight: Homeostasis, resilience and the Endocannabinoid System, a holistic approach to mitigate Covid-19 stress
  • 1.8 Insight: The role of the Endocannabinoid System in stress anxiety
Chapter 2: Therapeutic Aspects of the Cannabis Sativa L. Plant
  • 2.1 Medical Cannabis: General aspects
  • 2.2 How to use Medical Cannabis
  • 2.3 Pharmacology of tetrahydrocannabinol (THC). Can side effects be separated from therapeutic effects?
  • 2.4 Pharmacology of cannabidiol (CBD)
  • 2.5 Pharmacology of minor phytocannabinoids
  • 2.6 Insight: Cannabis, four new phytocannabinoids identified
  • 2.7 Insight: Heterologous production of cannabinoids
  • 2.8 Insight: Guide to delta-8-THC and delta-10-THC
  • 2.9 Insight: Not just cannabinoids, the link between tryptophan and cannabis
Chapter 3: Pathologies that Benefit from Therapeutic Cannabis
  • 3.1 Pathologies where Cannabis has shown therapeutic efficacy
  • 3.2 Cannabis in neurological and neurodegenerative diseases
  •             3.2.1 Parkinson’s disease and Cannabis
  •             3.2.2 Cannabis for Alzheimer’s and beyond: elderly, the clinical protocol
  • 3.2.3 Childhood epilepsy, cannabis-based therapies, and CBD side effects
  • 3.2.4 Cannabis and Multiple Sclerosis: analysis of major clinical trials
  • 3.3 Cannabis in disorders of the musculoskeletal system
  •             3.3.1 Medical Cannabis in orthopedics: cannabinoids and the musculoskeletal system
  •              3.3.2 Muscular Dystrophy and Cannabis
  •             3.3.3 Topical applications of CBD: transdermal patches with muscle relaxant effects
  •             3.3.4 CBD in the treatment of low back pain
  •             3.3.5 Insight: What are the effects of CBD? Can it be used in sports?
  • 3.4 Cannabis in cardiovascular disorders
  •             3.4.1 Cannabis and cardiovascular disease
  •             3.4.2 Cannabis and hypertension in elderly patients: a clinical study
  •             3.4.3 Cannabidiol for infants: ischemia and CBD
  • 3.5 Cannabis in metabolic disorders
  •             3.5.1 Cannabis and diabetes: pros and cons
  • 3.5.2 Cannabis and obesity: role of THCA
  • 3.6 Skin diseases and the Endocannabinoid System
  • 3.7 Cannabis and chronic inflammatory bowel disease (IBD)
  • 3.8 CBD in neuropsychiatry: the effects of Cannabidiol in the brain
  •             3.8.1 Post-Traumatic Stress and how Cannabis can help
  • 3.9 What is autism and how to treat it with CBD: two case studies from Brazil
  •             3.9.1 Hands-on experience: CBD in attention deficit hyperactivity disorder (ADHD)          
  •             3.9.2 Insights from MDs: Cannabinoids for Autism and ADHD
  • 3.10 Cannabis and glaucoma
  • 3.11 Burning Mouth and Cannabis
  • 3.12 Medical Cannabis and Palliative Care
  • 3.12.1 Cannabis and glioblastoma: tolerability and efficacy of Sativex®
  • 3.13 Cannabis in the treatment of migraine.
  • 3.14 The effects of Cannabis and phytocannabinoids on sleep and insomnia
  • 3.15 Drug interaction with cannabinoids
  • 3.16 Insight: Cannabis and cannabigerol (CBG) against antibiotic resistance
  • 3.17 Insight: Cannabis consumption, data from an American study
  • 3.18 Insight: CBD and Covid-19: the treatment of symptoms
  • 3.19 Insight: THC in the treatment of ARDS: possible role in COVID-19 infection?
Chapter 4: Medical Cannabis Regulation in Europe
  • 4.1 Premise
  • 4.2 Belgium
  • 4.3 Czech Republic
  • 4.4 Denmark
  • 4.6 Germany
  • 4.6 Italy
  • 4.7 Ireland
  • 4.8 Malta
  • 4.9 Portugal
  • 4.10 Sweden
  • 4.11 Switzerland
  • 4.12 UK
  • 4.13 Poland
Chapter 5: Conclusion
  • Conclusions & Closing Remarks

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Foreword by Daniele Piomelli, PhD

Daniele Piomelli - Cannabiscientia

Daniele Piomelli, PhD
University of California

[...] In Principles of Clinical Cannabinology, Cannabiscientia provides a comprehensive and easy-to-read guide to the clinical use of cannabis, covering its history, pharmacology, therapeutic applications, and potential benefits and drawbacks. They have in mind as readers healthcare professionals, students, researchers, and patients who seek to understand the science behind cannabis based medicine and its possible roles in treating a wide range of medical conditions. The book is organized in several chapters, each followed by a useful list of references to primary articles and reviews. Throughout the book, the authors draw on the latest scientific research and extensively on anecdotal evidence to present a view of cannabis that strives to be both balanced and objective. There is much still to learn about this complex plant, but this clear and well-written book will serve as a valuable resource for those seeking to understand it better. [...]  Read the full foreword »

30+ Pathologies covered

  • Parkinson’s disease 
  • Alzheimer’s disease
  • Childhood epilepsy
  • Multiple Sclerosis


  • Orthopedics
  • Muscular Dystrophy
  • Muscle relaxant effects
  • Low back pain


  • Cardiovascular disease
  • Hypertension in elderly patients
  • Ischemia in infants


  • Diabetes
  • Obesity


  • Glioblastoma


  • Post-Traumatic Stress Disorder










Or in alternative, start reading an extract of it!

Authored by experienced clinicians and scientists

  • Screenshot 2024-03-21 at 09.40.48

    Viola Brugnatelli,
    BSc Honours

  • Fabio-Turco-Cannabiscienza-e1624278504675-413x413-removebg-preview-q5j2hci3v13ynwte2uv6znhksy4iepjq6c4tsf1t3c-Jan-08-2024-01-04-03-7635-PM copy
    Fabio Turco, PhD
  • Marcello Albanesi - Cannabiscientia-1
    Marcello Albanesi, MD
  • Mauro Lins, MD
    Mauro Lins, MD
  • Fabio-Turco-Cannabiscienza-e1624278504675-413x413-removebg-preview-q5j2hci3v13ynwte2uv6znhksy4iepjq6c4tsf1t3c-Jan-08-2024-01-06-05-2075-PM
    Sandra Carrillo, MD
  • Carlo Privitera - Cannabiscientia
    Carlo Privitera, MD
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    Valeria Giorgi, PhD
  • Lorenzo Calvi, MD
    Lorenzo Calvi, MD
  • Mery J. Peña Guzman, MD
    Mery J. Peña Guzman, MD
  • Scicluna
    Jean Claude Scicluna, MD
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    Wendy Holden, MD
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    Janosch Kratz, MD

Product and Legislative Insights on 12 EU Countries

Insights on regulations, insurance reimbursement protocols and available products


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Principles of Clinical Cannabinology

Carefully curated clinical guidelines and case studies of experienced physicians from across the world.

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  • Ebook and paperback version available
  • 800+ scientific references
  • 600+ pages
  • 30+ pathologies 
  • 12 EU countries covered


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